报 告 人：井多辉，Dr. rer. Medic.
Children’s Cancer Institute, 澳大利亚
主 持 人：张超
时      间：2016年5月17日周二上午9:00-10:00
地      点：医学大楼1102 室

Biography
      Dr Duohui Jing graduated from Tsinghua University, China, and undertook PhD studies at Dresden University of Technology, Germany. In 2011, Dr Jing relocated from Germany to Australia and started his post-doctoral research on pediatric acute lymphoblastic leukemia (ALL) in Children's Cancer Institute, Australia. Now, he is leading the project on epigenetic mechanisms of glucocorticoid (chemo-drug) resistance in pediatric ALL using patient-derived xenograft model that is considered to be the most clinically relevant in vivo model. He has generated gene expression profiles and “epigenetic landscapes” of paediatric ALLs, and identified a novel epigenetic mechanism associated with glucocorticoid resistance. His recent Blood paper was the subject of an ‘Inside Blood’ commentary. Recently, Dr Jing was awarded Balnaves Foundation Young Researchers Fund 2016 and Cancer Institute NSW Early Career Fellowship 2016 – 2018. Moreover, Dr Jing is a core member of the Australian Association for Chinese Biomedical Scientists (AACBS), and aim to promote cross-cultural links between China and Australia.

Employment and Education

2011.1-present   Research Officer & CINSW Early Career Fellow, Children's Cancer Institute, Sydney, Australia.

2004.9-2010.8    Doctor rerum Medicinalium in Internal Medicine, Dresden University of Technology, Dresden, Germany

2000.9-2004.7    Bachelor of Science, Tsinghua University, China

Selected Publications

Jing D#, El-Hoss J#, et al. A single nucleotide polymorphism genotyping platform for the authentication of patient derived xenografts. Oncotarget 2016, under review. #, Co-First Authors.

Jing D, et al. Opposing regulation of BIM and BCL2 controls glucocorticoid-induced apoptosis of pediatric acute lymphoblastic leukemia cells. Blood. 2015;125(2):273-283.

Jing D, et al. Oxygen tension plays a critical role in the hematopoietic microenvironment in vitro. Haematologica 2012, 97:331-339

Jing D, et al. Hematopoietic stem cells in co-culture with mesenchymal stromal cells--modeling the niche compartments in vitro. Haematologica 2010, 95:542-550.