报告题目：Functional Genomics and Precision Medicine for Cancer Drug Discovery

报 告 人：李治中，Ph.D.
Genomics Institute of the Novartis Research Foundation, San Diego, California, USA
主 持 人：张 超 教授
时 间：2015年10月29日周四上午10:00-11:30
地 点：医学大楼1102室

Research Focus

Dr. Li’s research is focused on cancer biology and drug discovery

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  Large Scale functional pool shRNA and CRISPR screening of mRNA and LncRNAs in cancer and stem cells
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  High throughput genetic and drug combination screening in cancer and stem cells
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  Cancer heterogeneity and modeling

Employment and Education

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  2013-         Investigator, Genomics Institute of the Novartis Research Foundation
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  2010-2013 Presidential Postdoc Fellow, Novartis Institutes for Biomedical Research
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  2009-2010 Postdoc Fellow, Radiation Oncology, Duke University
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  2005-2009 Ph.D.in Cancer Biology, Duke University
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  2001-2005 B. S. in Biological Science and Biotechnology, Tsinghua University

Selected Publications

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  Gong C *, Li Z *, et al. A Long Non-coding RNA, LncMyoD, Regulates Skeletal Muscle Differentiation by Blocking IMP2-Mediated mRNA Translation. Developmental Cell. 2015
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  Li Z, Zhang Y. et al. Oncogenic NRAS, Required for Pathogenesis of Embryonic Rhabdomyosarcoma, Relies upon the HGA2–IGF2BP2 Pathway. Cancer Research. 2013
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  Li Z, Gilbert JA, Zhang Y. et al. An HMGA2-IGF2BP2 Axis Regulates Myoblast Proliferation and Myogenesis. Developmental Cell. 2012
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  Li Z, Rich JN. Et al. Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioblastoma Stem Cells. Cancer Cell. 2009(Cover Story)
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  Li Z（菠萝），癌症科普书《癌症.真相》，清华大学出版社，2015